South-South cooperation in combating antimicrobial resistance is experiencing a remarkable surge, exemplified by the launch of the IBSA-AMR Initiative (India-Brazil-South Africa) at the IBSA Forum in Pretoria in June 2026. This trilateral initiative aims to share technologies, expertise, and best practices among low- and middle-income countries, which collectively bear more than 70% of the global AMR burden. The IBSA-AMR Initiative is organized around three priority areas: transfer of rapid diagnostic technologies developed in India to African and Latin American laboratories, sharing of Brazilian antimicrobial stewardship protocols in agriculture with African Union member countries, and pooling of genomic surveillance data through a shared digital platform. South African Health Minister Dr. Joe Phaahla emphasized that "Global South countries share similar challenges in facing AMR: health systems under pressure, limited access to diagnostics, and unregulated antibiotic use. Our solutions must be co-created, not imported." He announced the establishment of a joint center of excellence based in Johannesburg. The initiative has also received technical support from WHO and the United Nations Development Programme (UNDP). An initial fund of $50 million, financed equally by the three founding countries, will support activities during the first three years. Other countries, including Nigeria, Indonesia, and Mexico, have expressed interest in joining the initiative.